Use of Recombinant Factor VIIa In Gastrointestinal Bleeding in Children with Malignancies: A Case Series
作者： Jan Hau Lee , Heng Joo Ng , Mei Yoke Chan
DOI: 10.1177/201010581001900211
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摘要: Recombinant factor VIIa (rFVIIa) may be useful in management of severe bleeding paediatric oncology patients. We described our experience and outcomes a form case series. In all cases, indication was massive gastrointestinal with haemodynamic instability, persistent thrombocytopenia coagulopathy despite correction. The range doses used 88–102 mcg/kg/dose. Each patient received at least 3 doses. use rFVIIa resulted reduction blood product support requirement. effective 2 out patients stopping the bleeding. There were no drug-related complications. has critical role to play early critically ill
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