METHODS FOR DETECTING AND SUPPRESSING ALIGNMENT ERRORS CAUSED BY FUSION EVENTS

摘要: Methods and systems for producing a filtered read sequence information data set by identifying one or more split reads in of test obtained from cell-free nucleic acid (cfNA) biological sample subject, wherein each comprises at least breakpoint; and, suppressing, the reads, (i) portion and/or that comprise variant within selected number nucleotides given breakpoint, thereby set, or, (ii) base calls set.