Glomerulonephritis with deposition of Australia antigen-antibody complexes in glomerular basement membrane.

作者: Burton Combes , James Shorey , Arnaldo Barrera , Peter Stastny , EdwinH. Eigenbrodt

DOI: 10.1016/S0140-6736(71)92572-4

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摘要: Abstract A patient with persistent Australia (Au) antigenaemia after post-transfusion hepatitis developed membranous glomerulonephritis. Immunofluorescent staining of kidney tissue revealed glomerular deposits IgG, complement C 3 , and Au antigen in a pattern characteristic immune complex deposition. These findings suggest that was involved the formation complexes whose deposition initiated pathologic process leading to development diffuse

参考文章(12)
Calderon Howe, David J. Gocke, Rapid Detection of Australia Antigen by Counterimmunoelectrophoresis Journal of Immunology. ,vol. 104, pp. 1031- 1032 ,(1970)
Saul Krugman, Infectious Hepatitis JAMA. ,vol. 200, pp. 365- 373 ,(1967) , 10.1001/JAMA.1967.03120180053006
DavidJ Gocke, Konrad Hsu, Councilman Morgan, Stephano Bombardieri, Michael Lockshin, CharlesL Christian, ASSOCIATION BETWEEN POLYARTERITIS AND AUSTRALIA ANTIGEN The Lancet. ,vol. 296, pp. 1149- 1153 ,(1970) , 10.1016/S0140-6736(70)90339-9
Frank J. Dixon, The pathogenesis of glomerulonephritis. The American Journal of Medicine. ,vol. 44, pp. 493- 498 ,(1968) , 10.1016/0002-9343(68)90050-8
BARUCH S. BLUMBERG, A Serum Antigen (Australia Antigen) in Down's Syndrome, Leukemia, and Hepatitis Annals of Internal Medicine. ,vol. 66, pp. 924- 931 ,(1967) , 10.7326/0003-4819-66-5-924
M. B. A. Oldstone, F. J. Dixon, Lymphocytic choriomeningitis: production of antibody by "tolerant" infected mice. Science. ,vol. 158, pp. 1193- 1195 ,(1967) , 10.1126/SCIENCE.158.3805.1193
Baruch S. Blumberg, A "New" Antigen in Leukemia Sera JAMA: The Journal of the American Medical Association. ,vol. 191, pp. 541- 546 ,(1965) , 10.1001/JAMA.1965.03080070025007
Roger D. Smith., J. Aquino, Viruses and the kidney. Medical Clinics of North America. ,vol. 55, pp. 89- 106 ,(1971) , 10.1016/S0025-7125(16)32545-7