作者: Eva Redei , Fraser Aird
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摘要: The invention features a substantially pure preparation of peptide having corticotropin release inhibiting factor (CRIF) activity comprising at least three contiguous amino acids contained within the acid sequence positioned between fourth and fifth thyrotropin releasing hormone (TRH) on prepro-TRH protein. CRIF further comprises uncleaved TRH portion terminus CRIF. Compositions, methods diagnosis treating related diseases are also included in invention.