Rheological analysis of itraconazole-polymer mixtures to determine optimal melt extrusion temperature for development of amorphous solid dispersion.

作者: Nayan Solanki , Simerdeep Singh Gupta , Abu T.M. Serajuddin

DOI: 10.1016/J.EJPS.2017.10.034

关键词:

摘要: The objective of this investigation was to develop a systematic method for the determination of optimal processing temperatures of drug-polymer mixtures for the development of …

参考文章(35)
Hemlata Patil, Roshan V. Tiwari, Michael A. Repka, Hot-Melt Extrusion: from Theory to Application in Pharmaceutical Formulation Aaps Pharmscitech. ,vol. 17, pp. 20- 42 ,(2016) , 10.1208/S12249-015-0360-7
Paul J. Flory, Principles of polymer chemistry ,(1953)
Simerdeep Singh Gupta, Anuprabha Meena, Tapan Parikh, Abu T. M. Serajuddin, Investigation of thermal and viscoelastic properties of polymers relevant to hot melt extrusion, I: Polyvinylpyrrolidone and related polymers Journal of Excipients and Food Chemicals. ,vol. 5, pp. 32- 45 ,(2014)
Abu T.M. Serajuddin, Solid dispersion of poorly water‐soluble drugs: Early promises, subsequent problems, and recent breakthroughs Journal of Pharmaceutical Sciences. ,vol. 88, pp. 1058- 1066 ,(1999) , 10.1021/JS980403L
W. -M. Kulicke, R. S. Porter, Relation between steady shear flow and dynamic rheology Rheologica Acta. ,vol. 19, pp. 601- 605 ,(1980) , 10.1007/BF01517513
Azita Saleki-Gerhardt, Claes Ahlneck, George Zografi, Assessment of disorder in crystalline solids International Journal of Pharmaceutics. ,vol. 101, pp. 237- 247 ,(1994) , 10.1016/0378-5173(94)90219-4
Ashish L. Sarode, Harpreet Sandhu, Navnit Shah, Waseem Malick, Hossein Zia, Hot melt extrusion (HME) for amorphous solid dispersions: Predictive tools for processing and impact of drug–polymer interactions on supersaturation European Journal of Pharmaceutical Sciences. ,vol. 48, pp. 371- 384 ,(2013) , 10.1016/J.EJPS.2012.12.012
Karel Six, Geert Verreck, Jef Peeters, Marcus Brewster, Guy Van den Mooter, Increased Physical Stability and Improved Dissolution Properties of Itraconazole, a Class II Drug, by Solid Dispersions that Combine Fast‐ and Slow‐Dissolving Polymers Journal of Pharmaceutical Sciences. ,vol. 93, pp. 124- 131 ,(2004) , 10.1002/JPS.10522
Simerdeep Singh Gupta, Tapan Parikh, Anuprabha K. Meena, Nidhi Mahajan, Imre Vitez, Abu T.M. Serajuddin, Effect of carbamazepine on viscoelastic properties and hot melt extrudability of Soluplus International Journal of Pharmaceutics. ,vol. 478, pp. 232- 239 ,(2015) , 10.1016/J.IJPHARM.2014.11.025
Huiju Liu, Xueyan Zhang, Herman Suwardie, Peng Wang, Costas G. Gogos, Miscibility Studies of Indomethacin and Eudragit® E PO by Thermal, Rheological, and Spectroscopic Analysis Journal of Pharmaceutical Sciences. ,vol. 101, pp. 2204- 2212 ,(2012) , 10.1002/JPS.23075