Oligoribonucleotides for cleaving RNA
作者： Stanley T. Crooke
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摘要: Oligomeric compounds including oligoribonucleotides and oligoribonucleosides are provided that have subsequences of 2-pentoribofuranosyl nucleosides activate dsRNase. The can include substituent groups for increasing binding affinity to complementary nucleic acid strand as well nuclease resistance. oligomeric useful diagnostics other research purposes, modulating the expression a protein in organisms, diagnosis, detection treatment conditions susceptible oligonucleotide therapeutics.
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