Antimicrobial Peptide LL-37 Facilitates Intracellular Uptake of RNA Aptamer Apt 21-2 Without Inducing an Inflammatory or Interferon Response.
作者： Tom Macleod , Joseph Ward , Adewonuola A. Alase , Charlie Bridgewood , Miriam Wittmann
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摘要: … dsRNA and producing crystalline structures that more effectively … The efficacy of these crystalline structures was found to … to form the correct crystal structure with LL-37 and so does not …
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sci-hub.se 参考文章(41)
Plinio Hurtado, Chen Au Peh, LL-37 Promotes Rapid Sensing of CpG Oligodeoxynucleotides by B Lymphocytes and Plasmacytoid Dendritic Cells The Journal of Immunology. ,vol. 184, pp. 1425- 1435 ,(2010) , 10.4049/JIMMUNOL.0902305
Marissa H. Braff, Mi‘i A. Hawkins, Anna Di Nardo, Belen Lopez-Garcia, Michael D. Howell, Cathy Wong, Kenneth Lin, Joanne E. Streib, Robert Dorschner, Donald Y. M. Leung, Richard L. Gallo, Structure-function relationships among human cathelicidin peptides: dissociation of antimicrobial properties from host immunostimulatory activities. Journal of Immunology. ,vol. 174, pp. 4271- 4278 ,(2005) , 10.4049/JIMMUNOL.174.7.4271
Özlem Cesur, Clare Nicol, Helen Groves, Jamel Mankouri, George Blair, Nicola Stonehouse, The Subcellular Localisation of the Human Papillomavirus (HPV) 16 E7 Protein in Cervical Cancer Cells and Its Perturbation by RNA Aptamers. Viruses. ,vol. 7, pp. 3443- 3461 ,(2015) , 10.3390/V7072780
Xue Chen, Toshiro Takai, Yang Xie, François Niyonsaba, Ko Okumura, Hideoki Ogawa, Human antimicrobial peptide LL-37 modulates proinflammatory responses induced by cytokine milieus and double-stranded RNA in human keratinocytes Biochemical and Biophysical Research Communications. ,vol. 433, pp. 532- 537 ,(2013) , 10.1016/J.BBRC.2013.03.024
CHENG YAO, JANG-HEE OH, DONG HUN LEE, JUNG-SOO BAE, CHENG LONG JIN, CHI-HYUN PARK, JIN HO CHUNG, Toll-like receptor family members in skin fibroblasts are functional and have a higher expression compared to skin keratinocytes. International Journal of Molecular Medicine. ,vol. 35, pp. 1443- 1450 ,(2015) , 10.3892/IJMM.2015.2146
Sabine Zahn, Claudia Rehkämper, Beate M. Kümmerer, Sandra Ferring-Schmidt, Thomas Bieber, Thomas Tüting, Jörg Wenzel, Evidence for a Pathophysiological Role of Keratinocyte-Derived Type III Interferon (IFNλ) in Cutaneous Lupus Erythematosus Journal of Investigative Dermatology. ,vol. 131, pp. 133- 140 ,(2011) , 10.1038/JID.2010.244
Rosella Doble, Michael F. McDermott, Özlem Cesur, Nicola J. Stonehouse, Miriam Wittmann, IL-17A RNA Aptamer: Possible Therapeutic Potential in Some Cells, More than We Bargained for in Others? Journal of Investigative Dermatology. ,vol. 134, pp. 852- 855 ,(2014) , 10.1038/JID.2013.399
Shin Morizane, Kenshi Yamasaki, Beda Mühleisen, Paul F. Kotol, Masamoto Murakami, Yumi Aoyama, Keiji Iwatsuki, Tissa Hata, Richard L. Gallo, Cathelicidin Antimicrobial Peptide LL-37 in Psoriasis Enables Keratinocyte Reactivity against TLR9 Ligands Journal of Investigative Dermatology. ,vol. 132, pp. 135- 143 ,(2012) , 10.1038/JID.2011.259
Prafullakumar Tailor, Tomohiko Tamura, Keiko Ozato, IRF family proteins and type I interferon induction in dendritic cells. Cell Research. ,vol. 16, pp. 134- 140 ,(2006) , 10.1038/SJ.CR.7310018
Akira Ishiguro, Taishin Akiyama, Hironori Adachi, Jun-Ichiro Inoue, Yoshikazu Nakamura, Therapeutic potential of anti–interleukin‐17A aptamer: Suppression of interleukin‐17A signaling and attenuation of autoimmunity in two mouse models Arthritis & Rheumatism. ,vol. 63, pp. 455- 466 ,(2011) , 10.1002/ART.30108