Respiratory Tissue Engineering: Current Status and Opportunities for the Future.

摘要: Currently, lung disease and major airway trauma constitute a global healthcare burden with limited treatment options. Airway diseases such as chronic obstructive pulmonary cystic fibrosis have been identified the fifth highest cause of mortality worldwide are estimated to rise fourth place by 2030. Alternate approaches therapeutic modalities urgently needed improve clinical outcomes for disease. This can be achieved through tissue engineering respiratory tract. Interest is growing in use tissue-engineered constructs both research tool, further our understanding pathology, validate new drugs, pave way novel drug therapies, also regenerative medical devices or an alternative transplant tissue. review provides concise summary field date. An initial overview anatomy physiology given, followed description stem cell po...