Sterol 14α-Demethylase Ligand-Binding Pocket-Mediated Acquired and Intrinsic Azole Resistance in Fungal Pathogens.
作者： Katharina Rosam , Brian C. Monk , Michaela Lackner
DOI: 10.3390/JOF7010001
关键词:
摘要: … p450 enzyme sterol 14α-demethylase CYP51 (synonym in molds; eg, Aspergillus), ERG11 (synonym in yeasts; eg, Candida spp.), or SDM (sterol 14α-demethylase; general term), a key …
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L. Joseph Wheat, Patricia Connolly, Melinda Smedema, P. David Rogers, Antifungal Drug Resistance in Histoplasmosis Humana Press. pp. 987- 992 ,(2009) , 10.1007/978-1-60327-595-8_21
Eveline Snelders, Simone M.T. Camps, Anna Karawajczyk, Antonius J.M.M. Rijs, Jan Zoll, Paul E. Verweij, Willem J.G. Melchers, Genotype-phenotype complexity of the TR46/Y121F/T289A cyp51A azole resistance mechanism in Aspergillus fumigatus. Fungal Genetics and Biology. ,vol. 82, pp. 129- 135 ,(2015) , 10.1016/J.FGB.2015.06.001
Yi-Chun Chen, Tzu-Yao Chang, Jien-Wei Liu, Fang-Ju Chen, Chun-Chih Chien, Chen-Hsiang Lee, Cheng-Hsien Lu, Increasing trend of fluconazole-non-susceptible Cryptococcus neoformans in patients with invasive cryptococcosis: a 12-year longitudinal study BMC Infectious Diseases. ,vol. 15, pp. 1- 7 ,(2015) , 10.1186/S12879-015-1023-8
Paul E. Verweij, Anuradha Chowdhary, Willem J. G. Melchers, Jacques F. Meis, Azole Resistance in Aspergillus fumigatus: Can We Retain the Clinical Use of Mold-Active Antifungal Azoles? Clinical Infectious Diseases. ,vol. 62, pp. 362- 368 ,(2016) , 10.1093/CID/CIV885
Alia A. Sagatova, Mikhail V. Keniya, Rajni K. Wilson, Brian C. Monk, Joel D. A. Tyndall, Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14α-Demethylase Antimicrobial Agents and Chemotherapy. ,vol. 59, pp. 4982- 4989 ,(2015) , 10.1128/AAC.00925-15
Hans J Cools, Bart A Fraaije, Update on mechanisms of azole resistance in Mycosphaerella graminicola and implications for future control. Pest Management Science. ,vol. 69, pp. 150- 155 ,(2013) , 10.1002/PS.3348
Laura Alcazar-Fuoli, Isabel Cuesta, Juan L. Rodriguez-Tudela, Manuel Cuenca-Estrella, Dominique Sanglard, Emilia Mellado, Three-dimensional models of 14α-sterol demethylase (Cyp51A) from Aspergillus lentulus and Aspergillus fumigatus: an insight into differences in voriconazole interaction International Journal of Antimicrobial Agents. ,vol. 38, pp. 426- 434 ,(2011) , 10.1016/J.IJANTIMICAG.2011.06.005
Steven Park, David S. Perlin, Establishing Surrogate Markers for Fluconazole Resistance in Candida albicans Microbial Drug Resistance. ,vol. 11, pp. 232- 238 ,(2005) , 10.1089/MDR.2005.11.232
Edward Sionov, Yun C. Chang, H. Martin Garraffo, Michael A. Dolan, Mahmoud A. Ghannoum, Kyung J. Kwon-Chung, Identification of a Cryptococcus neoformans Cytochrome P450 Lanosterol 14α-Demethylase (Erg11) Residue Critical for Differential Susceptibility between Fluconazole/Voriconazole and Itraconazole/Posaconazole Antimicrobial Agents and Chemotherapy. ,vol. 56, pp. 1162- 1169 ,(2012) , 10.1128/AAC.05502-11
Thomas Cairns, Emil G. Siegmund, Kin S. Chiu, Raymond Nelson, Residue characterization of triadimefon in grapes by gas chromatography and mass spectrometry/mass spectrometry. Journal of Mass Spectrometry. ,vol. 18, pp. 110- 115 ,(1989) , 10.1002/BMS.1200180205