Study on medical economic evaluation methods for metastatic brain tumors therapy

摘要: INTRODUCTION: Treatment design for metastatic brain tumors is required to firstly care about the life and function which patient hopes because it terminal care. Therefore, discuss value of therapy, a viewpoint QOL socioeconomic factors other than survival rate important. However, examination that applies these therapy needs be carried out more thoroughly. With this in mind, we cost effectiveness tumor, through pilot study on gamma knife therapy. MATERIALS AND METHOD: We studied 18 patients (mean age 61.6 years old) undergoing tumors. The health was assessed by profile-type measure SF-36 (Short-Form 36-Item Ver1.2) preference-based EQ-5D (EuroQoL-5D), before six months after Cost-utility-analysis (yen/Qaly) from quality adjusted (Qalys) medical fee claims. In addition, made correlation analysis irradiation procedure gains attained. RESULTS: observation useful tumor. As result, indicators showed increased mental (MH: p=0.040) role emotional (RE: p=0.029) with significant difference. measurement EQ-5D, added only one month based difference (p=0.022) pre-therapy QOL. utilities were analyzed became 0.052+/-0.175SD (score), Qalys 0.135. Because 721.4+/-5.2SD (thousand yen), performance cost-utility-analysis estimated as 5, 330, 000 (yen/Qaly). positive (r=0.845/p=0.034) found between utility score tumor energy (mJ), etc. CONCLUSION: established new over above mere concerning socioeconomics efficacy are difficult disease diseases. did clarifying compared factor. quantitatively, involved QOL, had improved. appropriate cover public insurance, under threshold line. Our also suggested that, when guessing prognosis, there should grades sensitivity according element