Seeding after radiofrequency ablation of hepatocellular carcinoma in patients with cirrhosis: a prospective study.

摘要: Abstract Background Neoplastic seeding of hepatocellular carcinoma may arise after radiofrequency ablation. Aims In order to clarify the real risk seeding, we observed a prospective cohort patients undergoing Methods Ninety-three (22.9%) out 406 consecutive with superimposed cirrhosis diagnosed at our Liver Unit (2000–2005) were selected for ablation according Barcelona 2000 EASL guidelines. Seventy-one treated by percutaneous approach and 22 laparotomy. After ultrasound scan was repeated every 3 months spiral-computed tomography 6 months. Results Overall 145 sessions performed in 93 patients: 113 (77.9%) 32 (22.1%) The median follow-up 23 (range 1–60). Only 1 71 (1.4%; 95% C.I. 0.25–7.56) percutaneously none (0%; 0–14.8) laparotomy showed neoplastic seeding. Conclusion experience small (1.1% per patient, 0.19–5.84; 0.7% procedure, 0.12–3.80). A stringent selection retraction needle hot tip have been instrumental obtaining this low frequency.