Association Between Dosage Frequency and the Treatment Outcomes of Sildenafil in Young and Middle-aged Men With Erectile Dysfunction: A Chinese, Multicenter, Observational Study.

摘要: Objective To evaluate the correlation between dosage frequency of sildenafil and its treatment outcomes in men with erectile dysfunction (ED). Methods Data were from a 4-week, multicenter, observational study (1699), 18 60 years age, clinical diagnosis ED defined as Sexual Health Inventory for Men (SHIM) score ≤21. The function quality sexual life evaluated at baseline endpoint (after 4 weeks) by using SHIM, Self-Esteem Relationship Questionnaire, 36-Item Short Form Survey, Erection Hardness Score, global efficacy question. Results Nine hundred thirty-five patients enrolled the ≤1 weekly, 573 2-3 158 4-7 weekly cohorts. After 4 weeks treatment, higher was associated better Survey score improvement (all P  = .04), whereas hypertension (odds ratio, 0.25; .05) are sensitive to treatment. Conclusion Higher is ED, concomitant hyperlipidemia recommended.