Multifocal motor neuropathy: lost in conduction block?

作者: Cindy Shin-Yi Lin

DOI: 10.1136/JNNP-2013-307200

关键词:

摘要: How to optimise intravenous immunoglobulin (IVIg) treatment? Should IVIg treatment strategies be tailor-made with the aid of biomarkers avoid habituation? There has been an exponential increase in usage for ever-growing number conditions. It is a product excellent safety record without side effects steroids or other immunosuppressive agents. Despite fact that there have numerous recent advances studying mechanisms action many conditions, still much learned. had major impact neurology, haematology, immunology, rheumatology and dermatology. However, limited by phenomenally expensive cost logistical problems associated its administration. Therefore, it important define therapeutic role. …

参考文章(10)
J P Azulay, P Rihet, J Pouget, F Cador, O Blin, J Boucraut, G Serratrice, Long term follow up of multifocal motor neuropathy with conduction block under treatment. Journal of Neurology, Neurosurgery, and Psychiatry. ,vol. 62, pp. 391- 394 ,(1997) , 10.1136/JNNP.62.4.391
A Ghosh, A Virgincar, R Kennett, M Busby, M Donaghy, The effect of treatment upon temporal dispersion in IvIg responsive multifocal motor neuropathy Journal of Neurology, Neurosurgery & Psychiatry. ,vol. 76, pp. 1269- 1272 ,(2005) , 10.1136/JNNP.2004.050252
E. A. Cats, W.- L. van der Pol, S. Piepers, H. Franssen, B. C. Jacobs, R. M. van den Berg-Vos, J. B. Kuks, P. A. van Doorn, B. G. van Engelen, J. J. Verschuuren, J. H. Wokke, J. H. Veldink, L. H. van den Berg, Correlates of outcome and response to IVIg in 88 patients with multifocal motor neuropathy Neurology. ,vol. 75, pp. 818- 825 ,(2010) , 10.1212/WNL.0B013E3181F0738E
Melvin Berger, Daniel E. McCallus, Cindy Shin‐Yi Lin, Rapid and reversible responses to IVIG in autoimmune neuromuscular diseases suggest mechanisms of action involving competition with functionally important autoantibodies Journal of The Peripheral Nervous System. ,vol. 18, pp. 275- 296 ,(2013) , 10.1111/JNS5.12048
E Nobile-Orazio, A Cappellari, N Meucci, M Carpo, F Terenghi, A Bersano, A Priori, S Barbieri, G Scarlato, Multifocal motor neuropathy: clinical and immunological features and response to IVIg in relation to the presence and degree of motor conduction block Journal of Neurology, Neurosurgery & Psychiatry. ,vol. 72, pp. 761- 766 ,(2002) , 10.1136/JNNP.72.6.761
Lotte Vlam, Elisabeth A Cats, Eline Willemse, Hessel Franssen, Jelena Medic, Sanne Piepers, Jan H Veldink, Leonard H van den Berg, W-Ludo van der Pol, Pharmacokinetics of intravenous immunoglobulin in multifocal motor neuropathy. Journal of Neurology, Neurosurgery, and Psychiatry. ,vol. 85, pp. 1145- 1148 ,(2014) , 10.1136/JNNP-2013-306227
M. C. Kiernan, J.-M. Guglielmi, R. Kaji, N. M. F. Murray, H. Bostock, Evidence for axonal membrane hyperpolarization in multifocal motor neuropathy with conduction block Brain. ,vol. 125, pp. 664- 675 ,(2002) , 10.1093/BRAIN/AWF041
E. Nobile-Orazio, C. Giannotta, L. Musset, P. Messina, J.-M. Leger, F. Gallia, R. G. Costa, Sensitivity and predictive value of anti-GM1/galactocerebroside IgM antibodies in multifocal motor neuropathy Journal of Neurology, Neurosurgery, and Psychiatry. ,vol. 85, pp. 754- 758 ,(2014) , 10.1136/JNNP-2013-305755
R. M. Van den Berg‐Vos, H. Franssen, J. H. J. Wokke, L. H. Van den Berg, Multifocal motor neuropathy: long-term clinical and electrophysiological assessment of intravenous immunoglobulin maintenance treatment. Brain. ,vol. 125, pp. 1875- 1886 ,(2002) , 10.1093/BRAIN/AWF193