Chemically-induced TLE models: Topical application.

摘要: Epilepsy is a condition of the brain that occurs in many different forms. For obvious reasons, understanding complex mechanisms underlying process epileptogenesis cannot be fully acquired clinical studies or analyses surgically resected human epileptic specimens. Accordingly, variety animal models have been developed recapitulate aspects various forms epilepsies. In our review we mainly focus on those chemically induced characteristics typically seen temporal lobe By comparing based topical application agents, advantages and disadvantages are discussed with respect to parameters including reliability mortality, as well similarity functional morphological alterations occurring regions course chronic state.