Analysis of low molecular weight compounds by MALDI-FTICR-MS
作者： Hao-Yang Wang , Xu Chu , Zhi-Xiong Zhao , Xiao-Shuang He , Yin-Long Guo
DOI: 10.1016/J.JCHROMB.2011.03.037
关键词:
摘要: This review focuses on recent applications of matrix-assisted laser desorption ionization-Fourier-transform ion cyclotron resonance mass spectrometry (MALDI-FTICR-MS) in qualitative and quantitative analysis low molecular weight compounds. The scope the work includes amino acids, small peptides, mono oligosaccharides, lipids, metabolic compounds, molecule phytochemicals from medicinal herbs even volatile organic compounds tobacco. We discuss both direct following derivatization. In addition we sample preparation strategies to reduce interferences m/z range improve sensitivities by derivatization with charge tags. also present coupling head space techniques MALDI-FTICR-MS. Furthermore, omics analyses based MALDI-FTICR-MS were discussed, including proteomics, metabolomics lipidomics, as well relative MS imaging for bio-active Finally, discussed investigations dissociation/rearrangement processes
elsevier.com
sci-hub.se 参考文章(203)
Jeffrey J. Jones, S. Mariccor A.B. Batoy, Charles L. Wilkins, A comprehensive and comparative analysis for MALDI FTMS lipid and phospholipid profiles from biological samples Computational Biology and Chemistry. ,vol. 29, pp. 294- 302 ,(2005) , 10.1016/J.COMPBIOLCHEM.2005.06.001
J. Fenn, M Mann, C. Meng, S. Wong, C. Whitehouse, Electrospray ionization for mass spectrometry of large biomolecules Science. ,vol. 246, pp. 64- 71 ,(1989) , 10.1126/SCIENCE.2675315
Vladimir M Doroshenko, Victor V Laiko, Nelli I Taranenko, Vadym D Berkout, H.Sang Lee, Recent developments in atmospheric pressure MALDI mass spectrometry International Journal of Mass Spectrometry. ,vol. 221, pp. 39- 58 ,(2002) , 10.1016/S1387-3806(02)00893-X
Daniel P. Little, Fred W. McLafferty, Sequencing 50-mer DNAs Using Electrospray Tandem Mass Spectrometry and Complementary Fragmentation Methods Journal of the American Chemical Society. ,vol. 117, pp. 6783- 6784 ,(1995) , 10.1021/JA00130A020
Harrison K. Musyimi, Damien A. Narcisse, Xia Zhang, Wieslaw Stryjewski, Steven A. Soper, Kermit K. Murray, Online CE-MALDI-TOF MS using a rotating ball interface. Analytical Chemistry. ,vol. 76, pp. 5968- 5973 ,(2004) , 10.1021/AC0489723
Mario Thevis, Andreas Thomas, Wilhelm Schänzer, Mass spectrometric determination of insulins and their degradation products in sports drug testing. Mass Spectrometry Reviews. ,vol. 27, pp. 35- 50 ,(2008) , 10.1002/MAS.20154
John R. Yates, Daniel Cociorva, Lujian Liao, Vlad Zabrouskov, Performance of a linear ion trap-Orbitrap hybrid for peptide analysis. Analytical Chemistry. ,vol. 78, pp. 493- 500 ,(2006) , 10.1021/AC0514624
Michael D. Leavell, Julie A. Leary, Fatty acid analysis tool (FAAT): An FT-ICR MS lipid analysis algorithm. Analytical Chemistry. ,vol. 78, pp. 5497- 5503 ,(2006) , 10.1021/AC0604179
James W. Hager, Recent trends in mass spectrometer development Analytical and Bioanalytical Chemistry. ,vol. 378, pp. 845- 850 ,(2004) , 10.1007/S00216-003-2287-1
Tammy LeRiche, Jens Osterodt, Dietrich A. Volmer, An experimental comparison of electrospray ion-trap and matrix-assisted laser desorption/ionization post-source decay mass spectra for the characterization of small drug molecules. Rapid Communications in Mass Spectrometry. ,vol. 15, pp. 608- 614 ,(2001) , 10.1002/RCM.278