Plasmin variants and uses thereof
作者： Hiroaki Tanaka , Stephane Bejanin
DOI:
关键词:
摘要: The invention concerns plasmin variants. Polynucleotides the disclosed variants are provided. Additionally, methods of using polynucleotides and provided herein.
lens.org 参考文章(23)
R. Swiercz, Rick Keck, E. Skrzypczak-Jankun, S. Selman, J. Jankun, Recombinant PAI-1 inhibits angiogenesis and reduces size of LNCaP prostate cancer xenografts in SCID mice. Oncology Reports. ,vol. 8, pp. 463- 470 ,(2001) , 10.3892/OR.8.3.463
Z.-Y. Tang, Q. Xue, D.-R. Shi, H.-Y. Song, H.-B. Tang, Q. Zheng, Invasion and metastasis of hepatocellular carcinoma in relation to urokinase-type plasminogen activator, its receptor and inhibitor. Journal of Cancer Research and Clinical Oncology. ,vol. 126, pp. 641- 646 ,(2000) , 10.1007/S004320000146
Christer Borgfeldt, Stefan R. Hansson, Barbro Gustavsson, Anna M�sb�ck, Bertil Cassl�n, Dedifferentiation of serous ovarian cancer from cystic to solid tumors is associated with increased expression of mRNA for urokinase plasminogen activator (uPA), its receptor (uPAR) and its inhibitor (PAI-1). International Journal of Cancer. ,vol. 92, pp. 497- 502 ,(2001) , 10.1002/IJC.1215
Hiroyuki Konno, Jinro Abe, Takeshi Kaneko, Megumi Baba, Atsushi Shoji, Kenichi Sunayama, Kinji Kamiya, Tatsuo Tanaka, Shohachi Suzuki, Satoshi Nakamura, Tetsumei Urano, Urokinase receptor and vascular endothelial growth factor are synergistically associated with the liver metastasis of colorectal cancer. Japanese Journal of Cancer Research. ,vol. 92, pp. 516- 523 ,(2001) , 10.1111/J.1349-7006.2001.TB01124.X
John Rømer, Thomas H. Bugge, Charles Fyke, Leif R. Lund, Matthew J. Flick, Jay L. Degen, Keld Danø, Impaired wound healing in mice with a disrupted plasminogen gene. Nature Medicine. ,vol. 2, pp. 287- 292 ,(1996) , 10.1038/NM0396-287
P. A. Andreasen, R. Egelund, H. H. Petersen, The plasminogen activation system in tumor growth, invasion, and metastasis. Cellular and Molecular Life Sciences. ,vol. 57, pp. 25- 40 ,(2000) , 10.1007/S000180050497
Hong Zhou, Peter Scott Mackie, Monique Louise Howard, Jane Lisette Fisher, Peter Fook Meng Choong, The expression of the urokinase plasminogen activator system in metastatic murine osteosarcoma: an in vivo mouse model. Clinical Cancer Research. ,vol. 7, pp. 1654- 1660 ,(2001)
Yoshiaki Toyama, Hideo Morioka, Tomoyuki Nakagawa, Hiroo Yabe, Takeshi Morii, Rikuo Yamada, Prognostic relevance of urokinase type plasminogen activator, its receptor and inhibitors in chondrosarcoma. Anticancer Research. ,vol. 20, pp. 3031- 3036 ,(2000)
Richard James Gilbert, Keith Martyn Dawson, Inhibitor resistant serine proteases ,(1993)
V. Ellenrieder, G. Adler, T.M. Gress, Invasion and metastasis in pancreatic cancer Annals of Oncology. ,vol. 10, pp. 46- 50 ,(1999) , 10.1093/ANNONC/10.SUPPL_4.S46