作者: Jan Balzarini , Sonsoles Velazquez , Maria Jose Camarasa
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摘要: A compound of the general formula (III): wherein X is O, S, NH or CH 2 ; Y S NH; Z R 1 C 1-8 alkyl, especially 1-6 preferably n-alkyl, e.g., n-pentyl n-hexyl; at least one and 3 H—[R 4 -R 5 ] n —R 6 —, in which: — comprises an oligopeptide, being amino acid selected from proline, alanine, hydroxyproline, dihydroxyproline, thiazolidinecarboxylic (thioproline), dehydroproline, pipecolic (L-homoproline), azetidinecarboxylic acid, aziridinecarboxylic glycine, serine, valine, leucine, isoleucine threonine, a neutral, non-polar moiety that bonded to by peptide bond, 1, 2, 3, 5; other ]n-R H; pharmaceutically acceptable salt thereof.