Biocompatible exosomes nanodrug cargo for cancer cell bioimaging and drug delivery.

作者: Aqsa Qambrani , Fawad ur Rehman , Tanziela Tanziela , Sana Shaikh , Semcheddine Farouk

DOI: 10.1088/1748-605X/ABAAA2

关键词:

摘要: Therapy against cancer still stays a daunting issue for human health, regardless of remarkable innovation in wide range pathology. In situ biosynthesized nanoclusters bestow novel remedy carcinogenic cell imaging. Exosomes have got special attention as an efficient tool the diagnosis various diseases, including cancers. All types cells (healthy or diseased) generate exosomes, making them significantly unique relevant disease and treatment. this contribution, we exploit possibility to utilize exosomes facilitate chemotherapeutics, viz combination doxorubicin (Dox) silver cells. Our study showed new facile way bioimaging using silver-DNA nanoclusters, thus further targeting drug delivery cargo. After isolating from neoplastic cells, i.e., HeLa, loaded with drug, treating other cargo isolated found that can readily enter targeted efficiently kill these This raises act modality target theranostics highly efficiency biocompability.

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