Experimental models and tools to tackle glioblastoma.

Patrick D. Hsu, Eric S. Lander, Feng Zhang, Development and applications of CRISPR-Cas9 for genome engineering. Cell. ,vol. 157, pp. 1262- 1278 ,(2014) , 10.1016/J.CELL.2014.05.010

Roger Stupp, Warren P. Mason, Martin J. van den Bent, Michael Weller, Barbara Fisher, Martin J.B. Taphoorn, Karl Belanger, Alba A. Brandes, Christine Marosi, Ulrich Bogdahn, Jürgen Curschmann, Robert C. Janzer, Samuel K. Ludwin, Thierry Gorlia, Anouk Allgeier, Denis Lacombe, J. Gregory Cairncross, Elizabeth Eisenhauer, René O. Mirimanoff, Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma The New England Journal of Medicine. ,vol. 352, pp. 987- 996 ,(2005) , 10.1056/NEJMOA043330

Robert M Bachoo, Elizabeth A Maher, Keith L Ligon, Norman E Sharpless, Suzanne S Chan, Mingjian James You, Yi Tang, Jessica DeFrances, Elizabeth Stover, Ralph Weissleder, David H Rowitch, David N Louis, Ronald A DePinho, Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell. ,vol. 1, pp. 269- 277 ,(2002) , 10.1016/S1535-6108(02)00046-6

Lionel M.L. Chow, Raelene Endersby, Xiaoyan Zhu, Sherri Rankin, Chunxu Qu, Junyuan Zhang, Alberto Broniscer, David W. Ellison, Suzanne J. Baker, Cooperativity within and among Pten, p53, and Rb Pathways Induces High-Grade Astrocytoma in Adult Brain Cancer Cell. ,vol. 19, pp. 305- 316 ,(2011) , 10.1016/J.CCR.2011.01.039

Brady Bernard, Chang-Jiun Wu, Giannicola Genovese, Ilya Shmulevich, Jill Barnholtz-Sloan, Lihua Zou, Rahulsimham Vegesna, Sachet A. Shukla, Giovanni Ciriello, W.K. Yung, Wei Zhang, Carrie Sougnez, Tom Mikkelsen, Kenneth Aldape, Darell D. Bigner, Erwin G. Van Meir, Michael Prados, Andrew Sloan, Keith L. Black, Jennifer Eschbacher, Gaetano Finocchiaro, William Friedman, David W. Andrews, Abhijit Guha, Mary Iacocca, Brian P. O’Neill, Greg Foltz, Jerome Myers, Daniel J. Weisenberger, Robert Penny, Raju Kucherlapati, Charles M. Perou, D. Neil Hayes, Richard Gibbs, Marco Marra, Gordon B. Mills, Eric Lander, Paul Spellman, Richard Wilson, Chris Sander, John Weinstein, Matthew Meyerson, Stacey Gabriel, Peter W. Laird, David Haussler, Gad Getz, Lynda Chin, Christopher Benz, Jill Barnholtz-Sloan, Wendi Barrett, Quinn Ostrom, Yingli Wolinsky, Keith L. Black, Bikash Bose, Paul T. Boulos, Madgy Boulos, Jenn Brown, Christine Czerinski, Matthew Eppley, Mary Iacocca, Thelma Kempista, Teresa Kitko, Yakov Koyfman, Brenda Rabeno, Pawan Rastogi, Michael Sugarman, Patricia Swanson, Kennedy Yalamanchii, Ilana P. Otey, Yingchun Spring Liu, Yonghong Xiao, J.Todd Auman, Peng-Chieh Chen, Angela Hadjipanayis, Eunjung Lee, Semin Lee, Peter J. Park, Jonathan Seidman, Lixing Yang, Raju Kucherlapati, Steven Kalkanis, Tom Mikkelsen, Laila M. Poisson, Aditya Raghunathan, Lisa Scarpace, Brady Bernard, Ryan Bressler, Andrea Eakin, Lisa Iype, Richard B. Kreisberg, Kalle Leinonen, Sheila Reynolds, Hector Rovira, Vesteinn Thorsson, Ilya Shmulevich, Matti J. Annala, Robert Penny, Joseph Paulauskis, Erin Curley, Martha Hatfield, David Mallery, Scott Morris, Troy Shelton, Candace Shelton, Mark Sherman, Peggy Yena, Lucia Cuppini, Francesco DiMeco, Marica Eoli, Gaetano Finocchiaro, Emanuela Maderna, Bianca Pollo, Marco Saini, Saianand Balu, Katherine A. Hoadley, Ling Li, C. Ryan Miller, Yan Shi, Michael D. Topal, Junyuan Wu, Gavin Dunn, Caterina Giannini, Brian P. O'Neill, B. Arman Aksoy, Yevgeniy Antipin, Laetitia Borsu, Samuel H. Berman, Cameron W. Brennan, Cameron W. Brennan, Roel G.W. Verhaak, Aaron McKenna, Benito Campos, Houtan Noushmehr, Sofie R. Salama, Siyuan Zheng, Debyani Chakravarty, J. Zachary Sanborn, Samuel H. Berman, Rameen Beroukhim, Wenbin Liu, Yuexin Liu, Yiling Lu, Gordon Mills, Alexei Protopopov, Xiaojia Ren, Youting Sun, Chang-Jiun Wu, W.K. Alfred Yung, Wei Zhang, Jianhua Zhang, Ken Chen, John N. Weinstein, Lynda Chin, Roel G.W. Verhaak, Houtan Noushmehr, Daniel J. Weisenberger, Moiz S. Bootwalla, Phillip H. Lai, Timothy J. Triche, David J. Van Den Berg, Peter W. Laird, David H. Gutmann, Norman L. Lehman, Erwin G. VanMeir, Daniel Brat, Jeffrey J. Olson, Gena M. Mastrogianakis, Narra S. Devi, Zhaobin Zhang, Darell Bigner, Eric Lipp, Roger McLendon, Ethan Cerami, Debyani Chakravarty, Giovanni Ciriello, Jianjiong Gao, Benjamin Gross, Anders Jacobsen, Marc Ladanyi, Alex Lash, Yupu Liang, Boris Reva, Chris Sander, Nikolaus Schultz, Ronglai Shen, Nicholas D. Socci, Agnes Viale, Martin L. Ferguson, Qing-Rong Chen, John A. Demchok, Laura A.L. Dillon, Kenna R. Mills Shaw, Margi Sheth, Roy Tarnuzzer, Zhining Wang, Liming Yang, Tanja Davidsen, Mark S. Guyer, Bradley A. Ozenberger, Heidi J. Sofia, Julie Bergsten, John Eckman, Jodi Harr, Jerome Myers, Christine Smith, Kelly Tucker, Cindy Winemiller, Leigh Anne Zach, Julia Y. Ljubimova, Greg Eley, Brenda Ayala, Mark A. Jensen, Ari Kahn, Todd D. Pihl, David A. Pot, Yunhu Wan, Jennifer Eschbacher, Greg Foltz, Nathan Hansen, Parvi Hothi, Biaoyang Lin, Nameeta Shah, Jae-geun Yoon, Ching Lau, Michael Berens, Kristin Ardlie, Rameen Beroukhim, Scott L. Carter, Andrew D. Cherniack, Mike Noble, Juok Cho, Kristian Cibulskis, Daniel DiCara, Scott Frazer, Stacey B. Gabriel, Nils Gehlenborg, Jeff Gentry, David Heiman, Jaegil Kim, Rui Jing, Eric S. Lander, Michael Lawrence, Pei Lin, Will Mallard, Matthew Meyerson, Robert C. Onofrio, Gordon Saksena, Steve Schumacher, Carrie Sougnez, Petar Stojanov, Barbara Tabak, Doug Voet, Hailei Zhang, Lihua Zou, Gad Getz, Nathan N. Dees, Li Ding, Lucinda L. Fulton, Robert S. Fulton, Krishna-Latha Kanchi, Elaine R. Mardis, Richard K. Wilson, Stephen B. Baylin, David W. Andrews, Larry Harshyne, Mark L. Cohen, Karen Devine, Andrew E. Sloan, Scott R. VandenBerg, Mitchel S. Berger, Michael Prados, Daniel Carlin, Brian Craft, Kyle Ellrott, Mary Goldman, Theodore Goldstein, Mia Grifford, David Haussler, Singer Ma, Sam Ng, Sofie R. Salama, J. Zachary Sanborn, Joshua Stuart, Teresa Swatloski, Peter Waltman, Jing Zhu, Robin Foss, Barbara Frentzen, William Friedman, Raquel McTiernan, Anthony Yachnis, D. Neil Hayes, Charles M. Perou, Siyuan Zheng, Rahulsimham Vegesna, Yong Mao, Rehan Akbani, Kenneth Aldape, Oliver Bogler, Gregory N. Fuller, The Somatic Genomic Landscape of Glioblastoma Cell. ,vol. 155, pp. 462- 477 ,(2013) , 10.1016/J.CELL.2013.09.034

E. C. Holland, W. P. Hively, R. A. DePinho, H. E. Varmus, A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice Genes & Development. ,vol. 12, pp. 3675- 3685 ,(1998) , 10.1101/GAD.12.23.3675

Marco Gallo, Jenny Ho, Fiona J. Coutinho, Robert Vanner, Lilian Lee, Renee Head, Erick K. M. Ling, Ian D. Clarke, Peter B. Dirks, A Tumorigenic MLL-Homeobox Network in Human Glioblastoma Stem Cells Cancer Research. ,vol. 73, pp. 417- 427 ,(2013) , 10.1158/0008-5472.CAN-12-1881

Houman D Hemmati, Ichiro Nakano, Jorge A Lazareff, Michael Masterman-Smith, Daniel H Geschwind, Marianne Bronner-Fraser, Harley I Kornblum, Cancerous stem cells can arise from pediatric brain tumors Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 15178- 15183 ,(2003) , 10.1073/PNAS.2036535100

Sheng Ding, Xiaohui Wu, Gang Li, Min Han, Yuan Zhuang, Tian Xu, Efficient Transposition of the piggyBac (PB) Transposon in Mammalian Cells and Mice Cell. ,vol. 122, pp. 473- 483 ,(2005) , 10.1016/J.CELL.2005.07.013

Rossella Galli, Elena Binda, Ugo Orfanelli, Barbara Cipelletti, Angela Gritti, Simona De Vitis, Roberta Fiocco, Chiara Foroni, Francesco Dimeco, Angelo Vescovi, Isolation and Characterization of Tumorigenic, Stem-like Neural Precursors from Human Glioblastoma Cancer Research. ,vol. 64, pp. 7011- 7021 ,(2004) , 10.1158/0008-5472.CAN-04-1364