Worm Venom Peptides

作者: WILLIAM R. KEM

DOI: 10.1016/B978-012369442-3/50060-X

关键词:

摘要: ABSTRACT Approximately half of the recognized animal phyla are worms. Many these groups receive little scientific attention except as they influence human affairs. Nevertheless, investigation substances that use to attack or defend against other organisms likely will provide useful molecular probes models for understanding complex physiological properties such membrane permeability and vulnerability exogenous agents toxins, infectious viruses, microbes, various parasites. Nemertines a phylum carnivorous marine worms produce plethora peptidic well alkaloidal toxins. While just few species have been investigated date, many toxins used chemical defense offense already discovered. Heteronemertines, which lack an armed proboscis, secrete small basic peptide neurotoxins larger cytolysins. The target ion channels involved in generating action potentials. Certain predatory annelids possess large protein stimulate neurotransmitter release at certain synapses by targeting particular calcium channels. Finally, parasitic (helminths nematodes) utilize cytolytic peptides aid digestion host cells tissues. This article summarizes current knowledge worm peptides.

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