Towards a non-invasive cardiac arrest monitor: An in vivo pilot study.

摘要: Abstract Introduction Hemodynamic-guided cardiopulmonary resuscitation (HGCPR) achieves better outcomes than standard resuscitation. Currently, HGCPR requires an invasive procedure, infeasible during Non-invasive measures of blood flow could provide useful hemodynamic guidance to rescuers. Objective We describe initial efforts develop a device that detects, analyzes, and the velocity carotid artery (CABF) towards brain at pre-arrest baseline (‘baseline’) resuscitation, here tested in swine model cardiac arrest (CA). A key element consists non-imaging diagnostic ultrasound, due its simplicity small form factor, hence potential for deployment bandage placed on neck. Methods Sixteen mixed-breed domestic were sedated, anesthetized paralyzed, followed by endotracheal intubation mechanical ventilation. Cardiac was induced with 3-s 100 mA transthoracic shock or bolus fentanyl, after which all animals received CPR. ultrasound probe manually applied neck over capture CABF baseline, as verified imaging, Results successfully collected measurements 14/16 attempted chest compression 5/16 swine. Signal characteristics include peak both (90.4 +/−20.4 cm/s) away from (−44.2 +/−31.8 cm/s) each larger (41.7+/−14.8 cm/s) (−3.0 +/−7.8 cm/s) baseline. Conclusion Measurement before CPR is feasible CA informative when achieved For example, observations reverse within merits further study prevalence effect outcomes. Also, tissue motion represents significant obstacle measurement Additional work will determine feasibility utility