Low prevalence of bloodstream infection and high blood culture contamination rates in patients with COVID-19.
作者： David Yu , Karolina Ininbergs , Karolina Hedman , Christian G. Giske , Kristoffer Strålin
DOI: 10.1371/JOURNAL.PONE.0242533
关键词:
摘要: Purpose In the management of COVID-19, knowledge is lacking on frequency secondary bacterial infections and how empirical antibiotic therapy should be used. In present study, we aimed to compare blood culture (BC) results a COVID-19 patient cohort with two cohorts patients without detected COVID-19. Methods Using retrospective study design subjected BC in six tertiary care hospitals, SARS-CoV-2 positive from March 1 April 30 2020 (COVID-19 group) were compared confirmed during same period (control group-2020) sampled 2019 group-2019). The outcomes studied proportion positivity, clinically relevant growth, contaminant growth. Results total 15,103 17,865 episodes studied. Clinically growth was 197/3,027 (6.5%) group 717/6,663 (10.8%) control group-2020 (p<0.0001) 850/8,175 (10.4%) group-2019 (p<0.0001). Contamination 255/3,027 (8.4%) 330/6,663 (5.0%) 354/8,175 (4.3%) (p<0.0001). Conclusion patients, prevalence bloodstream infection low contamination rate high. This influence guidelines regarding sampling patients.
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