[Repeated intraperitoneal injection of low-dose CDDP for gastric cancer with ascites owing to peritonitis carcinomatosa].

作者: Minoru Matsubara , Yasuyuki Araki , Masahiro Nakagawa , Motoki Ninomiya , Hirofumi Kawamoto

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摘要: We attempted treating 5 patients with ascites from peritonitis carcinomatosa of gastric carcinoma using TS-1 as systemic chemotherapy, and repeated intraperitoneal injection low-dose CDDP for the carcinomatous ascites. was administered in usual manner (10 mg/body) dissolved physiological saline 20-500 ml given an implantable reservoir. In 3 patients, disappeared, 2 other they decreased remarkably. As a result, QOL PS all were improved. Serum concentration suggested that weekly intraperitoneally injected not only has effect on carcinomatosa, but also functions modulator 5-FU.

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