Protecting Renal Blood Flow in the Intensive Care Unit

摘要: Acute renal failure (ARF) in the intensive care unit (ICU) represents a different spectrum of disease compared to ARF occurring outside ICU. As much as 95% ICU is secondary acute tubular necrosis (ATN). Incidence and mortality rates for are quite [1–3]. For example, incidence about 5% usually < 30%. However, ICU, can be high 15% with rate between 50% 90%. Severe (defined requiring dialysis) rarely occurs isolation, most often association multiple organ (MOF) [4]. Ischemia, principally medulla, estimated contribute 85% cases [5], causes medullary ischemia have been identified [6]. Most insults. Common conditions causing or exacerbating shown Table 1. Thus, it seems reasonable that preserving blood flow (RBF) should seen an imperative intensivist. Unfortunately, this goal easier espouse than achieve, increasing RBF may not always beneficial.