Endoscopic ultrasound-guided celiac plexus neurolysis for pancreatic cancer pain: a single-institution experience and review of the literature.

作者: Frederick J Meyers , Shiro Urayama , Quy N H Tran

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摘要: Pancreatic cancer is a common gastrointestinal malignancy with poor prognosis. The primary goal for caregivers effective pal- liative care, especially pain control, which routinely managed by ad- ministration of narcotic analgesics. An alternative or adjunctive modality celiac plexus neurolysis (CPN), safe and procedure. Recent advances in the use endoscopic ultrasonography (EUS) have made it an attractive guidance technique CPN while allowing simultane- ous tissue diagnosis. We report our experience using EUS-guided review available literature regarding this modality. neuropathic pancreatic carcinoma target palliation. Celiac (CPN) involves injection neurolytic agent (absolute alcohol, most commonly) into around to disrupt these impulses effectively control without noted side effects typical opi- oids. has been performed percutaneously under from fluoroscopy computed tomography (CT) at time laparotomy isolating artery injecting surrounding area. Common may include back abdominal (96%), di- arrhea (44%), postural hypotension (38%). 5 Rare complications such as paraplegia, bleeding, intestinal ischemia, pneumothorax, lumbar puncture reported depending on vari- approaches; causes are potentially sec- ondary imprecise identification radiologic anatomic landmarks, addition procedure-related structural injury extravasations agent.

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