PROFILES OF NON-CANCER DISEASES IN ATOMIC BOMB SURVIVORS

摘要: This article summarizes the results of a recent study atomic bomb radiation and non-cancer diseases in AHS (Adult Health Study) population by RERF (Radiation Effects Research Foundation) along with general discussion previous studies. The association CVD was examined incidence studies prevalence various endpoints atherosclerosis, such as MI, stroke, aortic arch calcification, isolated systolic hypertension, pulse wave velocity, and, although excess small, all indicated an increase heavily exposed group. Because consistency results, it is almost certain that higher among survivors. However, risk factors associated lifestyle had not necessarily been adjusted for to date, difficult at present conclude survivors direct effect radiation. Recent have demonstrated certainly uterine myoma more frequent It cannot, present, be concluded caused radiation, because there are no reported other populations. Further analyses including role confounding well molecular approaches needed verify this effect. relationship between exposure hyperparathyroidism can now said established view strong dose response, agreement populations, high younger survivors, biological plausibility. Future approaches, etc., determine pathogenic mechanism. Among benign tumours, response has tumours thyroid, stomach ovary. Although fewer conducted than cancer, clear emerging. Concerning chronic liver diseases, members significant response. Both hepatitis cirrhosis were suggested being exposure. possibility increased occurrence may due virus infection cannot excluded, ongoing C antibody titre awaited.