Pathways of Endocytosis in Thyroid Follicle Cells

摘要: Publisher Summary This chapter discusses that the thyroid gland maintains constant levels of hormones, thyroxine and triiodo thyronine, in circulation most mammalian species. ability is based on highly regulated sequence steps secretory process: Thyroglobulin, macromolecular product, precursor released stored follicle lumen where it remains segregated from extrafollicular space by a tight epithelial monolayer. Studies endocytosis cells require experimental access to luminal cell surface. has been accomplished past microinjection tracers into lumen. The suspensions inside-out follicles were used which apical plasma membranes directed toward culture medium separated junctions lateral surfaces. tightness monolayer stable polarity are prerequisites study selectively membrane. describes pathways with particular reference results obtained work follicles.