作者: Maria Kreuzberg , Michael Koslowski , Ozlem Tureci , Korden Walter , Ugur Sahin
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摘要: The invention relates to the treatment and/or prevention of tumor diseases associated with cells expressing CLDN6, in particular cancer and metastasis using antibodies which bind CLDN6. present application demonstrates that binding CLDN6 on surface is sufficient inhibit growth prolong survival extend lifespan patients. Furthermore, efficient inhibiting positive germ cell tumors such as teratocarcinomas or embryonal carcinomas, testis.