Prevalence of anti-tuberculosis drug resistance in an HIV/AIDS reference hospital in Rio de Janeiro, Brazil.
作者： A. Staviack , G. Werneck , G. Werneck , A. Marsico , M. A. Vieira
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摘要: CONTEXTE : Un hopital de reference pour la tuberculose (TB) et le virus l'immunodeficience humaine/ syndrome acquise (VIH/SIDA) dans cadre d'un programme lutte antituberculeuse a Rio Janeiro, Bresil. OBJECTIF Estimer prevalence resistance aux medicaments antituberculeux identifier les facteurs qui y sont associes. SCHEMA Etude transversale. On collige donnees cliniques laboratoire maniere retrospective entre 2001 2005. Ont ete consideres comme eligibles patients chez Mycobacterium tuberculosis isole disposaient des tests sensibilite medicaments. analyse par test Χ 2 , Mann-Whitney regression Poisson sur caracteristiques demographiques, risque resistance, serologie VIH antecedents TB. RESULTATS: Nous avons 350 traitements, dont 62 correspondaient ayant traites anterieurement Le statut positif 31,2% cas. trouve une 15,7% cas TB multiresistante 4,3% traitement anterieur (P < 0,01) rechute ans ont en association avec 0,03). Les cavites pulmonaires multiresistance 0,001). fait d'etre sans domicile tout type nouveaux 0,01). travailler l'hopital n'est pas associe resistance. CONCLUSION: Dans hopitaux il est necessaire suspecter maladie germes resistants La mise oeuvre efficient contre hospitaliere peut prevenir transmission meme un contexte elevee
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