Bacterial adhesins: function and structure.

作者: Per Klemm , Mark A. Schembri

DOI: 10.1016/S1438-4221(00)80102-2

关键词:

摘要: Specific adhesion to host tissue cells is an essential virulence factor of most bacterial pathogens. The fundamental processes that determine attachment surfaces are mediated by microbial adhesins. Host specificity and tropism characteristics exhibited different bacteria determined (at least in part) the interaction between adhesins their complementary receptors on cell surfaces. A detailed picture how able target various emerging. large number with individual receptor specificities have been identified. Furthermore, recent research has shown prone rapid microevolution results changes Microbial often assembled into complex polymeric organelle structures, however non-organelle linked surface as monomers or simple oligomers also exist. This review gives overview focuses some general aspects biogenesis role colonization factors.

参考文章(57)
Frederick C. Neidhardt, Escherichia coli and Salmonella :cellular and molecular biology : ASM Press. ,(2016)
Mark A. Schembri, Per Klemm, Heterobinary adhesins based on the Escherichia coli FimH fimbrial protein. Applied and Environmental Microbiology. ,vol. 64, pp. 1628- 1633 ,(1998) , 10.1128/AEM.64.5.1628-1633.1998
D C Dodd, P J Bassford, B I Eisenstein, Dependence of secretion and assembly of type 1 fimbrial subunits of Escherichia coli on normal protein export. Journal of Bacteriology. ,vol. 159, pp. 1077- 1079 ,(1984) , 10.1128/JB.159.3.1077-1079.1984
M A Lowe, S C Holt, B I Eisenstein, Immunoelectron microscopic analysis of elongation of type 1 fimbriae in Escherichia coli. Journal of Bacteriology. ,vol. 169, pp. 157- 163 ,(1987) , 10.1128/JB.169.1.157-163.1987