Chapter 8 Impacts of environmental toxicants and natural variables on the immune system of fishes

摘要: Publisher Summary This chapter presents some of the evidence for direct impacts individual environmental toxicants on cells immune system in fish. The is set mechanisms that protects host from microorganisms. Suppression renders susceptible to infection with pathogenic microorganisms or unable recognize and destroy have undergone neoplastic transformation. Environmental such as metals, pesticides, organics may induce immunosuppression. describes fish emphasizing aspects most relevant current immunotoxicology testing schemes. focuses effects metals organometals, pesticide, aromatic hydrocarbons, intracellular signaling events triggered by toxicant exposures. concludes a discussion evidences substantial oxygen pH system, arguing immunotoxic xenobiotics must be considered light variations well other natural stressors.