The energetic significance of lactate accumulation in blood at altitude.

摘要: The O2 equivalent of lactic acid accumulation in blood was estimated from data on ten subjects acclimatized to altitudes up 6500 m the course a Mt. Everest expedition. calculated value La by standard least squares regression 2.07 +/- 0.4 l for rise concentration [Lab] 1 g per liter (2.92 ml kg body weight mM increase lactate). This value, as well obtained procedure suggested Brace (2.84 0.5 l), not significantly different previously reported 2.38 0.22 (14) sea-level conditions. finding indicated that, after equilibrium is achieved, redistribution among extra- and intracellular compartments, reflected [Lab], appears be substantially affected chronic hypoxia. maximum debt values at base camp (5350 m) were 1.26 1.42 liters Caucasians Sherpas, respectively. amount measured altitude somewhat increased pure breathing (1.53 vs l).