Highly Sensitive, Automated Immunoassay for Immunoglobulin Free Light Chains in Serum and Urine

作者: Arthur R Bradwell , Hugh D Carr-Smith , Graham P Mead , Lian X Tang , Paul J Showell

DOI: 10.1093/CLINCHEM/47.4.673

关键词:

摘要: … onto 184-nm polystyrene latex particles (18). The latex-conjugated reagents were tested for … monoclonal gammopathies, in terms of improved sensitivity, accuracy, cost savings, and the …

参考文章(36)
James A. Goeken, Robert A. Kyle, David F. Keren, Peter D. Gorevic, Raymond Alexanian, Russell H. Tomar, Guidelines for Clinical and Laboratory Evaluation of Patients With Monoclonal Gammopathies Archives of Pathology & Laboratory Medicine. ,vol. 123, pp. 106- 107 ,(1999) , 10.1043/0003-9985(1999)123<0106:GFCALE>2.0.CO;2
R Jefferis, S Evans, N R Ling, J Lowe, D Hardie, Detection of free kappa chains in human serum and urine using pairs of monoclonal antibodies reacting with C kappa epitopes not available on whole immunoglobulins. Clinical and Experimental Immunology. ,vol. 52, pp. 234- ,(1983)
Abe, Goto, Kosaka, Wolfenbarger, Weiss, Solomon, Differences in kappa to lambda (kappa:lambda) ratios of serum and urinary free light chains Clinical and Experimental Immunology. ,vol. 111, pp. 457- 462 ,(1998) , 10.1046/J.1365-2249.1998.00487.X
E L Robinson, E Gowland, I D Ward, J H Scarffe, Radioimmunoassay of free light chains of immunoglobulins in urine. Clinical Chemistry. ,vol. 28, pp. 2254- 2258 ,(1982) , 10.1093/CLINCHEM/28.11.2254
Erika Bruck, National Committee for Clinical Laboratory Standards. Pediatrics. ,vol. 65, pp. 187- 188 ,(1980)
Thomas A. Waldmann, Warren Strober, R. Peter Mogielnicki, The renal handling of low molecular weight proteins Journal of Clinical Investigation. ,vol. 51, pp. 2162- 2174 ,(1972) , 10.1172/JCI107023
K. Söulling, Free light chains of immunoglobulins in normal serum and urine determined by radioimmunoassay. Scandinavian Journal of Clinical & Laboratory Investigation. ,vol. 35, pp. 407- 412 ,(1975) , 10.1080/00365517509095760
Mark Drayson, Lian X. Tang, Roger Drew, Graham P. Mead, Hugh Carr-Smith, Arthur R. Bradwell, Serum free light-chain measurements for identifying and monitoring patients with nonsecretory multiple myeloma Blood. ,vol. 97, pp. 2900- 2902 ,(2001) , 10.1182/BLOOD.V97.9.2900
K. Seoslling, Normal values for free light chains in serum in different age groups Scandinavian Journal of Clinical & Laboratory Investigation. ,vol. 37, pp. 21- 25 ,(1977) , 10.1080/00365517709108798