Preoperative bathing or showering with skin antiseptics to prevent surgical site infection.

摘要: Background: Surgical site infections (SSIs) are wound that occur after invasive (surgical) procedures. Preoperative bathing or showering with an antiseptic skin wash product is a well-accepted procedure for reducing bacteria (microflora). It less clear whether microflora leads to lower incidence of surgical infection. Objectives: To review the evidence preoperative antiseptics preventing hospital-acquired (nosocomial) infections. Search methods: For this fifth update we searched Cochrane Wounds Group Specialised Register (searched 18 December 2014); Central Controlled Trials (The Library 2014 Issue 11); Ovid MEDLINE (2012 Week 4 2014), (In-Process & Other Non-Indexed Citations 18, EMBASE 51), EBSCO CINAHL 2014) and reference lists articles. Selection criteria: Randomised controlled trials comparing any preparation used full-body non-antiseptic preparations in people undergoing surgery. Data collection analysis: Two authors independently assessed studies selection, risk bias extracted data. Study were contacted additional information. Main results: We did not identify new inclusion update. Seven involving total 10,157 participants included. Four included had three comparison groups. The all was 4% chlorhexidine gluconate (Hibiscrub/Riohex). Three 7791 compared placebo. Bathing placebo result statistically significant reduction SSIs; relative SSI (RR) 0.91 (95% confidence interval (CI) 0.80 1.04). When only high quality comparison, RR 0.95 (95%CI 0.82 1.10). 1443 bar soap chlorhexidine, when combined there no difference SSIs (RR 1.02, 95% CI 0.57 1.84). 1192 patients washing, one large study found favour 0.36, 95%CI 0.17 0.79). smaller between who washed those preoperatively. Authors' conclusions: This provides benefit over other products, reduce Efforts nosocomial infection should focus on interventions where effect has been demonstrated.