Efficacy and safety of manidipine in patients with hypertension aged 70 years or older

摘要: This study aimed to assess the efficacy and safety of manidipine in patients with hypertension aged 70 years or older. For this purpose, a 6-month was performed. A total 48 (mean age: 80.5 ± 7.1 years; 33.3% male) were included. The most common comorbidity diabetes (39.6%). Manidipine 10 mg/day prescribed 72.9% 20 27.1% patients. Treatment associated significant decrease blood pressure, from 163.3 12.7/88.8 9.6 mmHg 147.8 10.0/80.3 6.4 (p < 0.01). Microalbuminuria reduced 27.1 8.3% during = 0.004). Barthel index Get Up Go test results remained unchanged, whilst there not improvement Pfeiffer’s test. administration safe (only one patient left study) effective since pressure decreased significantly poorly controlled group hypertensive (89% over 75 58% ...