Acute effects of intravenous cyclosporine on blood pressure, renal hemodynamics, and urine prostaglandin production of healthy humans.

作者: MATTHEW R. WEIR , DAVID K. KLASSEN , STEVE Y. SHEN , DEBORA SULLIVAN , E. ULRIC BUDDEMEYER

DOI: 10.1097/00007890-199001000-00009

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摘要: The acute renal failure associated with cyclosporine may result from vasoconstriction of intrarenal arterioles. To evaluate the mechanism cyclosporine-induced nephrotoxicity, we acutely administered to eight healthy female volunteers normal blood pressure and function. Cyc

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