Translating Lung Function Genome-Wide Association Study (GWAS) Findings: New Insights for Lung Biology.

作者: A.K. Kheirallah , S. Miller , I.P. Hall , I. Sayers

DOI: 10.1016/BS.ADGEN.2015.12.002

关键词:

摘要: … -wide association studies (GWAS) have been successful at detecting multiple loci harboring variants predicting the variation in lung function … tissue and specific gene knockout mice is a …

参考文章(202)
Maria Hukkinen, Jaakko Kaprio, Ulla Broms, Anne Viljanen, Daniel Kotz, Taina Rantanen, Tellervo Korhonen, Heritability of lung function: a twin study among never-smoking elderly women. Twin Research and Human Genetics. ,vol. 14, pp. 401- 407 ,(2011) , 10.1375/TWIN.14.5.401
Dawn L. DeMeo, Thomas J. Mariani, Christoph Lange, Sorachai Srisuma, Augusto A. Litonjua, Juan C. Celedón, Stephen L. Lake, John J. Reilly, Harold A. Chapman, Brigham H. Mecham, Kathleen J. Haley, Jody S. Sylvia, David Sparrow, Avrum E. Spira, Jennifer Beane, Victor Pinto-Plata, Frank E. Speizer, Steven D. Shapiro, Scott T. Weiss, Edwin K. Silverman, The SERPINE2 Gene Is Associated with Chronic Obstructive Pulmonary Disease American Journal of Human Genetics. ,vol. 78, pp. 253- 264 ,(2006) , 10.1086/499828
Michael H Cho, Merry-Lynn N McDonald, Xiaobo Zhou, Manuel Mattheisen, Peter J Castaldi, Craig P Hersh, Dawn L DeMeo, Jody S Sylvia, John Ziniti, Nan M Laird, Christoph Lange, Augusto A Litonjua, David Sparrow, Richard Casaburi, R Graham Barr, Elizabeth A Regan, Barry J Make, John E Hokanson, Sharon Lutz, Tanda Murray Dudenkov, Homayoon Farzadegan, Jacqueline B Hetmanski, Ruth Tal-Singer, David A Lomas, Per Bakke, Amund Gulsvik, James D Crapo, Edwin K Silverman, Terri H Beaty, None, Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis The Lancet Respiratory Medicine. ,vol. 2, pp. 214- 225 ,(2014) , 10.1016/S2213-2600(14)70002-5
Osamu Hori, Jerold Brett, Timothy Slattery, Rong Cao, Jinghua Zhang, Jing Xian Chen, Mariko Nagashima, Erik R. Lundh, Sharmila Vijay, Di Nitecki, John Morser, David Stern, Ann Marie Schmidt, The Receptor for Advanced Glycation End Products (RAGE) Is a Cellular Binding Site for Amphoterin MEDIATION OF NEURITE OUTGROWTH AND CO-EXPRESSION OF RAGE AND AMPHOTERIN IN THE DEVELOPING NERVOUS SYSTEM Journal of Biological Chemistry. ,vol. 270, pp. 25752- 25761 ,(1995) , 10.1074/JBC.270.43.25752
Sreekumar G. Pillai, Dongliang Ge, Guohua Zhu, Xiangyang Kong, Kevin V. Shianna, Anna C. Need, Sheng Feng, Craig P. Hersh, Per Bakke, Amund Gulsvik, Andreas Ruppert, Karin C. Lødrup Carlsen, Allen Roses, Wayne Anderson, Stephen I. Rennard, David A. Lomas, Edwin K. Silverman, David B. Goldstein, , A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci PLOS Genetics. ,vol. 5, ,(2009) , 10.1371/JOURNAL.PGEN.1000421
M A Hofmann, S Drury, B I Hudson, M R Gleason, W Qu, Y Lu, E Lalla, S Chitnis, J Monteiro, M H Stickland, L G Bucciarelli, B Moser, G Moxley, S Itescu, P J Grant, P K Gregersen, D M Stern, A M Schmidt, RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response. Genes and Immunity. ,vol. 3, pp. 123- 135 ,(2002) , 10.1038/SJ.GENE.6363861
Daan W Loth, María Soler Artigas, Sina A Gharib, Louise V Wain, Nora Franceschini, Beate Koch, Tess D Pottinger, Albert Vernon Smith, Qing Duan, Chris Oldmeadow, Mi Kyeong Lee, David P Strachan, Alan L James, Jennifer E Huffman, Veronique Vitart, Adaikalavan Ramasamy, Nicholas J Wareham, Jaakko Kaprio, Xin-Qun Wang, Holly Trochet, Mika Kähönen, Claudia Flexeder, Eva Albrecht, Lorna M Lopez, Kim de Jong, Bharat Thyagarajan, Alexessander Couto Alves, Stefan Enroth, Ernst Omenaas, Peter K Joshi, Tove Fall, Ana Viñuela, Lenore J Launer, Laura R Loehr, Myriam Fornage, Guo Li, Jemma B Wilk, Wenbo Tang, Ani Manichaikul, Lies Lahousse, Tamara B Harris, Kari E North, Alicja R Rudnicka, Jennie Hui, Xiangjun Gu, Thomas Lumley, Alan F Wright, Nicholas D Hastie, Susan Campbell, Rajesh Kumar, Isabelle Pin, Robert A Scott, Kirsi H Pietiläinen, Ida Surakka, Yongmei Liu, Elizabeth G Holliday, Holger Schulz, Joachim Heinrich, Gail Davies, Judith M Vonk, Mary Wojczynski, Anneli Pouta, Åsa Johansson, Sarah H Wild, Erik Ingelsson, Fernando Rivadeneira, Henry Völzke, Pirro G Hysi, Gudny Eiriksdottir, Alanna C Morrison, Jerome I Rotter, Wei Gao, Dirkje S Postma, Wendy B White, Stephen S Rich, Albert Hofman, Thor Aspelund, David Couper, Lewis J Smith, Bruce M Psaty, Kurt Lohman, Esteban G Burchard, André G Uitterlinden, Melissa Garcia, Bonnie R Joubert, Wendy L McArdle, A Bill Musk, Nadia Hansel, Susan R Heckbert, Lina Zgaga, Joyce B J van Meurs, Pau Navarro, Igor Rudan, Yeon-Mok Oh, Susan Redline, Deborah L Jarvis, Jing Hua Zhao, Taina Rantanen, George T O'Connor, Samuli Ripatti, Rodney J Scott, Stefan Karrasch, Harald Grallert, Nathan C Gaddis, John M Starr, Cisca Wijmenga, Ryan L Minster, David J Lederer, Juha Pekkanen, Ulf Gyllensten, Harry Campbell, Andrew P Morris, Sven Gläser, Christopher J Hammond, Kristin M Burkart, John Beilby, Stephen B Kritchevsky, Vilmundur Gudnason, Dana B Hancock, O Dale Williams, Ozren Polasek, Tatijana Zemunik, Ivana Kolcic, Marcy F Petrini, Matthias Wjst, Woo Jin Kim, David J Porteous, Generation Scotland, Blair H Smith, Anne Viljanen, Markku Heliövaara, John R Attia, Ian Sayers, Regina Hampel, Christian Gieger, Ian J Deary, H Marike Boezen, Anne Newman, Marjo-Riitta Jarvelin, James F Wilson, Lars Lind, Bruno H Stricker, Alexander Teumer, Timothy D Spector, Erik Melén, Marjolein J Peters, Leslie A Lange, R Graham Barr, Ken R Bracke, Fien M Verhamme, Joohon Sung, Pieter S Hiemstra, Patricia A Cassano, Akshay Sood, Caroline Hayward, Josée Dupuis, Ian P Hall, Guy G Brusselle, Martin D Tobin, Stephanie J London, Genome-wide association analysis identifies six new loci associated with forced vital capacity Nature Genetics. ,vol. 46, pp. 669- 677 ,(2014) , 10.1038/NG.3011
Jacek Majewski, Tomi Pastinen, The study of eQTL variations by RNA-seq: from SNPs to phenotypes Trends in Genetics. ,vol. 27, pp. 72- 79 ,(2011) , 10.1016/J.TIG.2010.10.006
Harvey W. Smith, Chris J. Marshall, Regulation of cell signalling by uPAR Nature Reviews Molecular Cell Biology. ,vol. 11, pp. 23- 36 ,(2010) , 10.1038/NRM2821
Sven Heinz, Christopher Benner, Nathanael Spann, Eric Bertolino, Yin C. Lin, Peter Laslo, Jason X. Cheng, Cornelis Murre, Harinder Singh, Christopher K. Glass, Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities Molecular Cell. ,vol. 38, pp. 576- 589 ,(2010) , 10.1016/J.MOLCEL.2010.05.004