Successful treatment of invasive aspergillosis in a heart transplant patient

作者: O. U. J. Okereke , D. A. Cooley , L. O. Gentry , B. Radovancevic , O. H. Frazier

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摘要: Infection continues to be a major cause of mortality in cardiac transplant patients, and even though there has been significant progress diagnosing treating many infectious disease problems, invasive aspergillosis the patient represents serious usually fatal complication. Even with successful early diagnosis, use free amphotericin B (a polyene antibiotic) failed cure disseminated infection. We report case 46-year-old who respond treatment after 7-day period for biopsy-proven pulmonary aspergillosis. However, subsequent substitution liposomal form was used, responded well total dose 1.5 mg. After 7 months, This experience suggests that introduction may give new hope an otherwise lethal

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