Characterization of blood redox status of early and mid-late lactating dairy cows

摘要: The effect of the stage lactation on blood redox homeostasis bovine and buffalo cows was eval- uated. investigation carried out early lactating mid-late cows, reared in a farm located Campania (southern Italy). Plasma concentration α-tocopherol ascorbate, total antioxidant capacity (TAC), glutathione peroxidase (GPx), superoxide dismutase activities were higher (P < 0.01) lac - tating thus suggesting consumption antioxidants during lactation. protein-bound carbonyls (PC) nitrotyrosine (N-Tyr), level lipid hydroperoxides (LPO) that peroxidation peroxynitrite production are crucial determining oxidative modifications plasma. TAC positively correlated with ascorbate 0.03), negatively PC 0.002), 0.03) group. These findings demonstrate circulating plays major role preventing protein induced by carbonyls, scavenging is impaired We calculated stress index as ratio (PC + N-Tyr)/TAC multiplied 100, we found this parameter 0.0001) cows. Therefore, it could be useful for assessing extent damage relation to whole status. Further, suggest LPO/GPx 100 might used This represent standard evaluating depending deficiency enzymatic defence. parameters proposed possible effective description physiological changes associated