Decreased cariogenicity of a mutant of Streptococcus mutans.

摘要: A strain of Streptococcus mutans was treated with a mutagenic agent. This resulted in isolation mutant which, compared to the original strain, had lost ability form sticky deposits on hard surfaces sucrose medium. Apart from colonial morphology, not changed any other characteristic studied. In 9-week experiment SPF Syrian hamsters average caries score induced by significantly lower than that parent strain. 5-week using germfree rats, virtually its cariogenicity sharp contrast Strep, mutans. all instances implanted microorganisms could be recovered animals during phases experiments.