Potential applications of gene therapy to the treatment of intervertebral disc disorders.

作者: Kotaro Nishida , Lars G. Gilbertson , Paul D. Robbins , Christopher H. Evans , James D. Kang

DOI: 10.1097/00003086-200010001-00031

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摘要: Gene therapy involves the transfer of genes to cells such that recipient express these and thereby synthesize ribonucleic acid protein they encode. Recent investigations suggest gene may have potential applications in treatment intervertebral disc disorders, particularly those associated with degeneration. The successful vivo therapeutic target within clinically relevant animal models is one example rapid progress being made. purpose current review address several important technical issues, including choice vectors delivery strategy characteristics tissues, which are future clinical for disorders. It already apparent from growing literature has becoming a valuable mode disorders twenty-first century.

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