RNA viruses redirect host factors to better amplify their genome.

摘要: Publisher Summary This chapter provides an updated view of the host factors that are, at present, believed to participate in replication/transcription RNA viruses. One major hurdles faced when attempting identify specifically involved viral is how discriminate these from those translation. Several shown affect synthesis are known be protein synthesis, for example, translation factors. In addition, some identified date appear influence amplification as well and replication frequently tightly associated. specific actively participating transcription/replication have been regions protein/replicase or protein/viral interaction determined. The centers exclusively on functionally important amplification. It presents a list viruses which factor associates with polymerase, affecting genome also indicates usually accepted cell function polymerase subunit binds.