作者: Laurie A. Boyer , Robert R. Latek , Craig L. Peterson
DOI: 10.1038/NRM1314
关键词:
摘要: Chromatin-remodelling complexes have an important role in all DNA-mediated processes and, although much is known about how these enzymes regulate chromosomal DNA accessibility, they interact with their histone substrates has remained unclear. However, recent studies indicated that the SANT domain a central chromatin remodelling by functioning as unique histone-interaction module couples binding to enzyme catalysis.