[2] Cultured S49 mouse T lymphoma cells

摘要: Publisher Summary This chapter focuses on S49 mouse T cell lymphoma cells that are adapted to grow in culture. It has characteristics of general utility investigators who make use cultured cells. The quickly with a generation time approximately 16 hr. They have stable near-euploid karyotype. stirred or stationary suspension described the ones might appeal investigators, otherwise indifferent particular nature line, seeking desirable technical properties. addition special properties almost certainly reflect those normal population which arose. concludes discussion mutagenesis generally increases frequency and predetermines mutations selectable genes. describes mutagen screening system utilizing distinguishes classes mutagenic mechanisms—in particular, lead base substitution frameshift alterations.