Is CD133 the Appropriate Stem Cell Marker for Glioma?
作者： Zarine Khan , Leroy Shervington , Amal Shervington
DOI: 10.1007/978-94-007-1709-1_13
关键词:
摘要: Stem cells have been accredited for their contribution towards tissue repair and regeneration, however, potential to cause cancer is given more attention. CD133, a glioma stem cell marker has linked brain tumour proliferation multi-drug resistance. Failure of CD133+ define relapse an effective forming ability CD133– enhances the need identify selective reliable marker. This review focuses on undifferentiated differentiated aspects involving embryonic markers Oct4A BMP2. In addition, alternative molecular targets enlisted that may help further locate eliminate tumour-initiating cells, thereby increasing effectiveness therapeutic drugs used cure glioma.
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