Morphological changes in osteosarcoma after chemotherapy--COSS 80.

摘要: Forty-five osteosarcomas were investigated by special methods such as preparation of undecalcified bone tumor tissue, imprint cytology, histochemistry, and quantitative analysis. The morphological regression grades their relation to chemotherapy are reported Salzer-Kuntschik et al. (1983). results presented demonstrate that smaller respond more favorably than larger tumors. function bone-tumor cells, e.g., osteoid production, trabecular formation, mineralization, seems be important for the sensitivity cell polymorphism. estimation morphology in at least two total areas is essential borderline cases (grade III/grade IV). Imprint cytology very helpful rapid effect therapy demonstration cellular At moment, we not able determine from first biopsy before starting chemotherapy.