Modulation of a Fronto-Parietal Network in Event-Based Prospective Memory: An rTMS Study.

摘要: Abstract Event-based prospective memory (PM) is a multi-component process that requires remembering the delayed execution of an intended action in response to pre-specified PM cue, while being actively engaged ongoing task. Some neuroimaging studies have suggested both prefrontal and parietal areas are involved maintenance realization intentions. In present study, transcranial magnetic stimulation (TMS) was used investigate causal involvement frontal different stages (in particular, target checking intention retrieval), determine specific contribution these regions performance. Our results demonstrate repetitive TMS (rTMS) interferes with performance when applied at 150–350 ms right dorsolateral cortex (DLPFC), 400–600 ms left posterior (PPC). The study provides clear evidence DLPFC plays crucial role early components (target checking), PPC seems be mainly later processes, such as retrieval action.