Lung transplantation in patients over the age of 50

摘要: It is common to assign an upper age limit for potential lung transplant recipients. The influence of on LTX outcome is, however not, documented. A review our first 103 LTXs, 51 single LTXs and 52 double includes 31 recipients aged 50-63 years (mean 55.3 +/- 3.9); 19 received LTX, 12 LTX. Indications in those greater than 50 included proportionately more patients with emphysema interstitial disease. Actuarial survivals less at 12, 36, 60 months were 68%, 60%, 55%, was 70%, 61%, respectively. causes death reflect a tendency younger die from graft rejection older sepsis. Acute 6 weeks posttransplant chronic frequent (P < 0.05). 6-minute walk modified Bruce protocol tests, the incidence CMV pneumonitis, late post-LTX renal function not related age. In conclusion, carefully selected candidates their sixth seventh decades, acceptable operation end-stage lower allograft (acute or chronic) may decreased immunological responsiveness