Anti-microbial agents

摘要: Antimicrobial agents that can serve as replacements to conventional pharmaceutical antibiotics are disclosed. The antimicrobial comprise conjugatively transmissible plasmids kill targeted pathogenic bacteria, but not harmful donor bacteria. Two types of lethal One type kills recipient bacteria by unchecked ('runaway') replication in the cells and is prevented from occuring cells. Another expressing a gene produces product detrimental or bacterial cells, being expression