Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
作者： Anne Brunet , Lora B Sweeney , J Fitzhugh Sturgill , Katrin F Chua , Paul L Greer
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摘要: … the FOXO family of Forkhead transcription factors (5, 14, 15). We hypothesized that, in higher organisms, FOXO … affect various FOXO target genes, we found that SIRT1 repressed FOXO-…
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